http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007066589-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7efe8b4bde054992136f5f672b868213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48d857ada705bd1e63053fc52ad41ac6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2911261e48bfb53215227cd4d0a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1e424c631b32e4a18b52a545917f103 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 |
| filingDate | 2003-11-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2e75662177fc56a91a5a9415b6b8f81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_848ed3c885da32c946332eaa52297fdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ab76de393e49dd009f2e8173522c147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_628b4ef5d96385e6fa1adc454efe59c7 |
| publicationDate | 2007-03-22^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2007066589-A1 |
| titleOfInvention | Method of preparing 10th-dibenzo[b,f][11,4]thiazepin-11-one |
| abstract | Disclosed is a method of preparing 10H-dibenzo[b,f][1,4]thiazepin-11-one, including reacting dithiosalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution in the presence or absence of a reducing agent, to prepare 2-(2-nitrophenylsulfuryl)benzoic acid; subjecting the 2-(2-nitrophenylsulfuryl)benzoic acid to nitro group reduction in the presence of hydrogen, a solvent and a heterogeneous metal catalyst, to prepare 2-(2-aminophenylsulfuryl)benzoic acid; and directly cyclizing the 2-(2-aminophenylsulfuryl)benzoic acid in an organic solvent in the presence or absence of an acid catalyst. The method according to the present invention is economical due to the use of the inexpensive starting material, and also environmentally friendly and efficient by minimizing the use of the organic solvent and performing direct cyclization without the activation of carboxylic acid. |
| priorityDate | 2002-11-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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