Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ca732aeee5a5bf121e816bc2036c77b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate |
2007-10-30^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a221ef1274f1ec6aed3ba50e7c4d08e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa423a2e0d21218fb84f1e1abd41a4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f7dff0e109a9ef44a2ea744b5a8791 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f2f21253104f35705f3c99668d1d813 |
publicationDate |
2008-02-28^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008050364-A1 |
titleOfInvention |
Treatment of LFA-1 Associated Disorders with Increasing Doses of LFA-1 Antagonist |
abstract |
A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose. |
priorityDate |
1999-03-19^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |