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filingDate 2007-10-30^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a221ef1274f1ec6aed3ba50e7c4d08e7
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publicationDate 2008-02-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2008050364-A1
titleOfInvention Treatment of LFA-1 Associated Disorders with Increasing Doses of LFA-1 Antagonist
abstract A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
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