abstract |
The present invention relates to pyridinone derivatives of formula (I): n n n n n n n n n n wherein Z represents C 2-6 alkynyl, aryl or heteroaryl, any of which groups may be optionally substituted, and R 1 represents hydrogen, C 1-6 alkyl, C 3-7 heterocycloalkyl(C 1-6 )alkyl, di(C 1-6 )alkylamino(C 1-6 )alkyl, C 2-6 alkylcarbonyloxy(C 1-6 )alkyl or C 3-7 cycloalkoxycarbonyloxy(C 1-6 )alkyl, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C virus infections. |