http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008268056-A1

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filingDate 2007-04-26^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-10-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2008268056-A1
titleOfInvention Injectable copolymer hydrogel useful for repairing vertebral compression fractures
abstract Embodiments of the present invention provide a biocompatible substance useful for repairing a vertebral compression fracture (VCF). The biocompatible substance can be made from two or more biocompatible polymeric hydrogels via physical cross-linking. The biocompatible substance thus made exhibits a lower critical solution temperature (LCST) phenomenon and undergoes volume and stage changes with temperature in the range of 25° C.-34° C. The biocompatible substance can be in liquid injectable form at room temperature, can cure within the human body without damaging living tissues, does not release toxic monomers during surgery, and, once cured, has optimum mechanical properties that match those of a human cancellous bone. It can be used alone in minimally invasive procedures or in combination with other spine treatments.
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