abstract |
Pharmaceutical compositions containing as an active ingredient compounds of the general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them and exhibiting thrombopoietin receptor agonism: n X 1 —Y 1 -Z 1 -W 1 (I) n wherein X 1 is optionally substituted aryl, optionally substituted heteroaryl or the like; Y 1 is —NR A CO—(CH 2 ) 0-2 — or the like (wherein R A is a hydrogen or the like); Z 1 is optionally substituted phenylene or the like; and W 1 is a group represented by the below formula: n n n n n n n n n n wherein R 1 , R 2 , R 3 , and R 4 are each independently a hydrogen atom, optionally substituted lower alkyl or the like, a broken line (---) represents the presence or absence of bond. |