| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7084 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 |
| filingDate |
2008-01-28^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9202d2ccddab0a65d3c5a43cdec9a344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0d48869f3ac89f3e392e547c1c17412 |
| publicationDate |
2010-02-25^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010047177-A1 |
| titleOfInvention |
Methods and compositions for treating neuropathies |
| abstract |
Methods of treating or preventing axonal degradation in neuropathic diseases and neurological disorders in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts at least in part by increasing sirtuinAMPK activity, LKB 1 activity and/or CaMKKβ activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons, alone or in combination with agents that act by other mechanisms. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing such neuropathies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11414407-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9844561-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4233878-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10323058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189872-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233207-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10925888-B2 |
| priorityDate |
2007-01-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |