| abstract |
The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: n n n n n n n n n n Wherein X, Z, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , n and m are as defined herein. Also disclosed herein are the methods of preparation of compounds of formula (I), intermediates therefor and their utility in treating a variety of disease conditions. |