| abstract |
A continuous Glomerular Filtration Rate (GFR) estimation system may include a Foley catheter, a continuous urine creatinine sensor, and a urine output monitor. The continuous GFR estimation system computes creatinine clearance as CrCl=(U cr ×U vol )/(P cr ×I mim ), where U cr is urine creatinine in mg/dL, U vol is urine volume in mL, P cr is plasma (serum) creatinine in mL, and I min is time in minutes. A Foley catheter may be used to withdraw urine from the bladder. The urine may be delivered to a urine output monitor that provides the U vol value over a time I min . Attached to the catheter is the flow-through continuous urine creatinine sensor for providing the U cr value. The remaining parameter is P cr . Because serum creatinine levels do not change rapidly over time, a blood sample may be withdrawn prior to the start of the continuous GFR to obtain the P C r value. |