Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81075572b8d1526ce20dbf5dd7dbded8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 |
filingDate |
2007-03-21^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab1f7dd8e2539f6b6242947462b27af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38aeeb230d3d120cf39930eb54283267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84df5cb936d3a03efe1d33cf6773bef9 |
publicationDate |
2010-07-15^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010179332-A1 |
titleOfInvention |
Process for the purification of ropinirole hydrochloride |
abstract |
The present invention provides an improved process for the purification of ropinirole hydrochloride. The process includes (i) treating ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent; (ii) triturating the ropinirole hydrochloride obtained in step (i) with ethanol; (iii) reacting the triturated solid with base in water immiscible solvent and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010249433-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7968731-B2 |
priorityDate |
2006-03-29^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |