| abstract |
The present invention relates to an enzyme substrate for detecting nitroreductase activity of formula (I) below: n n n n n n n n n n in which X is S, NX1, O or NX1-CO; R1 is nothing or a substituent selected from Cl, CH 3 , Br, F, I, alkyl, aryl and carboxyl; R2 is nothing or a substituent selected from Cl, O—CH 2 —O, O—CH 3 , F, diethylenediamine-CH 3 , NR3R4, Br, I, alkyl, aryl, carboxyl, NO 2 and n n n n n n n n n n R3 and R4 are independently H or an alkyl group containing from 1 to 4 carbon atoms; and X1 is selected from H, CH 3 , C 2 H 4 Ph, OH, alkyl and aryl. |