| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1355b1b5342fae39b8e2e5c444b6ad0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33719806a38887178ded280fd6d90b8a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2010-03-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c96b5b39641fc0811dee61a027d5f4c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72f84a2eaed5013507f4a54ab4f41d84 |
| publicationDate |
2010-09-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010233728-A1 |
| titleOfInvention |
Method and kit for detecting the early onset of renal tubular cell injury |
| abstract |
A method and kit for detecting the early onset of renal tubular cell injury, utilizing NGAL as an early urinary biomarker. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctate cytoplasmic distribution reminiscent of a secreted protein. The appearance NGAL in the urine is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9534027-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8592170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010233739-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10829525-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9624281-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010233740-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012068545-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011091912-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730790-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10588937-B2 |
| priorityDate |
2003-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |