http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010278733-A1

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filingDate 2007-05-22^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1c0d83a5fb25aac992ebac13638b0b7
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publicationDate 2010-11-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2010278733-A1
titleOfInvention Composition for diagnosis of amyloid-related disease
abstract There is provided a composition comprising a compound represented by general formula (I), wherein R l represents a 5-iodothiophen-2-yl group or the like, and R 2 represents a 4-dimethylaminophenyl group or the like. This composition is useful for diagnosis of an amyloid-related disease such as Alzheimer's disease because the compound has high binding specificity to amyloid β protein, high permeability through the blood-brain barrier, and a property of being rapidly eliminated from sites other than senile plaques in the brain.
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