Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 |
filingDate |
2010-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15aa615cbdc2d7673837884ea1560545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_720780e663f20854254e953d62fa9d18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_067687fc00a02f7f68e76f0cd1e3a8eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9c36b5969f9d0c8dc7f92aa9b93a4c0 |
publicationDate |
2011-01-27^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011020385-A1 |
titleOfInvention |
COMBINATIONS OF PNEUMOCOCCAL RrgB CLADES |
abstract |
Pneumococcal pilus subunit RrgB has at least three clades. Serum raised against a given clade is active against pneumococci which express that RrgB clade, but is not active against strains which express one of the other two clades i.e. there is intra-clade cross-protection, but not inter-clade cross-protection. Thus an immunogenic composition can include at least two different clades of RrgB to improve strain coverage against pilus-containing pneumococci. These multiple clades may be present in the immunogenic composition as separate polypeptides or may be fused as a single polypeptide chain. |
priorityDate |
2009-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |