| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56541df79a26070c6c2c585b54af47c5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate |
2008-10-03^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2416dd68e1f7cfdc241ec937b0bf775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2eaf75d154a0fda0ba1a41b181dd27 |
| publicationDate |
2011-05-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011117588-A1 |
| titleOfInvention |
Method of predicting drug-induced phospholipidosis |
| abstract |
The present invention provides a method of predicting drug-induced phospholipidosis, comprising a step of contacting a mammalian cell with a test compound, a step of measuring extracellular and/or intracellular lysosomal enzyme level or activity, or measuring intracellular LC3 level, and a step of selecting a test compound that has enhanced extracellular secretion of the enzyme or increased the protein level as a compound capable of inducing drug-induced phospholipidosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9841426-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015219654-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10401361-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018214813-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018213389-A1 |
| priorityDate |
2007-10-04^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |