| abstract |
A peptide or peptide derivative comprising: n n n n n n n n n (i) WDLYFEIVW; n (SEQ ID NO: 1) n n n n n n n n n (ii) a variant amino acid sequence comprising one, two, three or four L-amino acid substitutions in WDLYFEIVW (SEQ ID NO: 1); or n (iii) the retro-inverso variant of the peptide or peptide derivative of either one of parts (i) and (ii),n nwherein said peptide or peptide derivative has procoagulant activity.n n n n A peptide or peptide derivative comprising:n (i) an amino acid sequence comprising imfwydcye; or (ii) a variant amino acid sequence comprising one, two, three, four, five or six amino acid substitutions in imfwydcye,n nwherein said peptide or peptide derivative has procoagulant activity. |