http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012286781-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dda2cbe0891915189d8157f9275e47a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5601
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5605
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-565
filingDate 2012-04-16^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de58d579ead0728436126298378958ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e574484764ff5934446c42c3502dd2f0
publicationDate 2012-11-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2012286781-A1
titleOfInvention Magnetic Resonance Methodology for Imaging of Exchange-Relayed Intramolecular Nuclear Overhauser Enhancement Effects in Mobile Solutes
abstract An embodiment in accordance with the present invention provides a method for imaging exchange-relayed intramolecular Nuclear Overhauser Enhancement (NOE) effects with Magnetic Resonance (MR) in mobile solutes. In the method, non-exchangeable protons or other magnetic nuclei with resonances of a finite linewidth in the NMR proton spectrum within a species or subject can be labeled magnetically using radiofrequency. Intramolecular NOE effects can then transfer the label between the non-exchangeable nuclei and non-exchangeable and exchangeable protons in the same molecule during a magnetic steady state. The water signal is monitored to observe a reduction in the water signal due to the transfer of NOE labels to the water signal in a manner relayed through the exchangeable protons. Analysis can also be performed to produce an image or spectrum of the subject.
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priorityDate 2011-04-15^^<http://www.w3.org/2001/XMLSchema#date>
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