http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012301401-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d926e19fd225fce5b4b8497a2721a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98d479908db8fc36f6e2895fc094666d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cc35e3210aa5ca04e64447359cfe3b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84ba8ad05866aa606a7e6b2d6abe83b2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D323-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D323-00 |
filingDate | 2010-11-25^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbca99e0b0fffb728354251158367e68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42fa49cff88f75b86a3450234017290f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c1cf3952f654795146ce5e56c666793 |
publicationDate | 2012-11-29^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2012301401-A1 |
titleOfInvention | Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions |
abstract | This invention relates to A crown ether of formula (I) n n n n n n n n n n wherein m is 4, 5, 6, 7, or 8 and i is, independently for each occurrence, 1 or 2; each occurrence of R 1 and R 2 is independently selected from hydrogen; linear or branched and substituted or unsubstituted C 1 to C 10 alkyl, alkenyl and alkinyl; and substituted or unsubstituted aryl with up to 10 ring atoms; or R 1 and R 2 together form an oxo group; at least one occurrence in the crown ether of R 1 , R 2 and the carbon to which R 1 and R 2 are attached, said carbon being bound directly to an ether oxygen of formula (I), form together a group of formula (II) n n n n n n n n n n wherein L is a linker which is absent or selected from a covalent bond and (CR 5 R 6 ) n , each occurrence of R 5 and R 6 being independently selected from hydrogen; linear or branched and substituted or unsubstituted C 1 to C 10 alkyl, alkenyl and alkinyl; and substituted or unsubstituted aryl with up to 10 ring atoms, n being 1, 2 or 3; X and Y, independently from each other, are selected from O and S; Z, independently for each occurrence, is absent or an electron-withdrawing group; R 3 and R 4 , independently for each occurrence, are selected from hydrogen; linear or branched and substituted or unsubstituted C 1 to C 10 alkyl, alkenyl and alkinyl; substituted or unsubstituted aryl with up to 10 ring atoms; H(OCH 2 CH 2 ) k - and H(OCH 2 CH 2 ) k O—, wherein k is an integer number from 1 to 10; wherein substituents, if present, are selected from OH, O—CH 3 and halogens. |
priorityDate | 2009-11-25^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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