http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013115709-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4057201a18a81a6545075b591fa765ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a647f5089bb2d552d7f8f2a7f04ad9e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cded1dd9dcc9dac6c1d9e44d8c1f78f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-361 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2011-06-28^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a94795672db9e2f8d9fea926ebd9445e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68307da49d56c98a29cc949391dc9240 |
| publicationDate | 2013-05-09^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2013115709-A1 |
| titleOfInvention | Chromatography method and media used therefore |
| abstract | The present invention relates to a method for running ion exchange chromatography on a media comprising shell beads having an inner porous core and an outer shell, wherein the inner core is provided with ligands whose charge changes with pH and the shell is provided with charged ion exchange ligands, the method comprising the following steps: a) adsorbing sample molecules on the shell ligands at a first pH; b) causing a discharge of the inner core ligands at a second pH by addition of a buffer substance that is able to increase its charge having the same sign/type as that of the core ligands, which at the same time causes release of ions from the inner core ligands and thereby an increase in ionic strength that displaces the sample molecules from the shell ligands i.e. causes an elution. |
| priorityDate | 2010-07-09^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 20 of 20.