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filingDate 2012-03-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c28147ee7d32e102529ec34fafdeaead
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publicationDate 2014-01-09^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014010839-A1
titleOfInvention Method of screening antiretroviral compounds and vaccine
abstract The present invention relates to an in vitro method of screening for candidate compounds capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus in which the candidate compound which modulates the expression and/or the activity of the SAMHD1 protein is identified as a candidate compound capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus. n The invention also relates to a vaccine composition and an immunogenic composition, comprising i) an inhibitor of the expression and/or of the activity of the SAMHD1 protein and ii) at least one antigen of a retrovirus.
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25939
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8HYB1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID405790
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ60440
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP11052
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25477
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID31931

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