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filingDate 2011-03-14^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-01-23^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014024132-A1
titleOfInvention Methods and systems using integrated metabolomics and pharmacokinetics for multi-component drug evaluation
abstract Disclosed are methods and systems for identifying biochemical changes in a subject in response to administration of a multi-component therapeutic and one or more active ingredients in the multi-component therapeutic. The methods and systems of the invention may be used to elucidate the interaction of the biological system's genome with its environments, and in the pharmacokinetic, pharmacodynamic and toxicology analysis of multi-component therapeutics. The metabolomics methods and systems of the invention can also be used in studies of plant derived agents to demonstrate biochemical alterations in response to the dynamic multi-component intervention.
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