| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a909431ec0911da8737981ebf0950b1b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6862
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6855
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2012-05-17^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcc777ef8a6b1bb263431c8af4e82919
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c8b6bdc2a1a4aed280f874604684519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a19d7cdda086efe80c2a3fcfb7b58103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f88462ec83af9563fce70954113a54f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e90a8ace0cdfd725648235526a6edda |
| publicationDate |
2014-06-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014171338-A1 |
| titleOfInvention |
Methods and compositions for detecting target nucleic acids |
| abstract |
The present invention provides compositions, apparatuses and methods for detecting one or more nucleic acid targets present in a sample. Methods of the invention include utilizing two or more ligation probes that reversibly bind a target nucleic acid in close proximity to each other and possess complementary reactive ligation moieties. When such probes have bound to the target in the proper orientation, they are able to undergo a spontaneous chemical ligation reaction that yields a ligation product that is directly detected or that is amplified to produce amplicons that are then detected. The present invention also provides methods to stabilize sample RNA so that degradation does not significantly affect the results of the analysis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016297778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10683534-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021108370-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019046768-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3325669-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10510435-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457980-B2 |
| priorityDate |
2011-05-17^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |