| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ff1670d045a89199c267573a776df87 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2013-03-06^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aceb4dc00f7b0da873f1bf8bbdc24c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab01825d2f493d7cc5474b06d56899d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e91373a48de43737322c4befe6c3114
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2624dadffd4c834be8cbdefba9cbedda |
| publicationDate |
2015-02-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015045251-A1 |
| titleOfInvention |
Duplex chromogenic assay for in situ detection of nucleic acids |
| abstract |
The disclosure provides methods of detecting two or more target nucleic acids. The methods can include the steps of contacting a sample with two or more label probes having distinct enzyme labels and targeting distinct nucleic acid targets, binding the two or more label probes to the target nucleic acids by hybridization; contacting the sample with a first substrate for the first enzyme of the first label probe; reacting the first substrate with the first enzyme, thereby producing a first detectable signal; contacting the sample with a second substrate for the second enzyme of the second label probe; reacting the second substrate with the second enzyme, thereby producing a second detectable signal; and detecting the first detectable signal and the second detectable signal, thereby detecting the first and second target nucleic acids in the sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11530269-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019199643-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9315854-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023014825-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11078528-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4063519-A1 |
| priorityDate |
2012-03-06^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |