| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce3d57a6fc2fad533ce367f648d280ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8528ff66470c896b6da8ed059464e31f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2014-10-03^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cdb6ee3509e0d1dad75b7cc7cf7dd9f |
| publicationDate |
2015-02-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015045369-A1 |
| titleOfInvention |
Novel markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the dna base excision repair pathway |
| abstract |
Described are mismatch repair (MMR-)deficient tumors. Markers are presented herein having a high sensitivity to detect whether a tumor is mismatch repair deficient or not. The markers are particularly mutations in microsatellite regions. Accordingly, methods and materials are provided for diagnosing microsatellite instability of a tumor. Such a method comprises determining the presence of these markers. Further, kits are provided to detect the presence of these markers (or subsets thereof) in a sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021183683-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10633707-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10699802-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11104938-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294529-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114182012-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2609117-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023140875-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018237088-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110797080-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111373050-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018037231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114182011-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11519021-B2 |
| priorityDate |
2012-04-10^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |