Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cce74ae91129e276612f5855529149a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fc9ac5b1a1c0d3567c0ac2f4a62a671 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2f19a1643f4a3456adc0c187030413e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_beaa69dd9cc534fa853442eef87c3ab8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-06113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-3577 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-3577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
filingDate |
2013-08-20^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67013d99bf2643e99efae31da2486e97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f92062793657489867b1b2590d31639d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d8091df8d87c085cec0469fa0ef01f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b23abdd94c9ea72170f3e14fb2c5989a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f7ebaf8df1037c1f5ebd9233ed1688a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4594c2690b77ff41f2e8e3a811edec2 |
publicationDate |
2015-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015211988-A1 |
titleOfInvention |
Raman, infrared, or raman-infrared analysis of peripheral blood plasma protein structure and its relation to cognitive development in alzheimer's disease |
abstract |
The present invention relates to a Raman spectroscopy method for determining protein structure associated with global cognitive deterioration in Alzheimer's disease from the Raman spectroscopic analysis of a human blood sample, preferably of a human blood plasma sample, comprising obtaining at least one spectral value of at least one of the Raman spectrum regions comprised between 1600-1700 cm −1 , between 910-980 cm −1 , between 730-760 cm −1 and/or between 390-450 cm −1 , and where said spectral value allows obtaining an indication of the presence or absence of protein structure associated with a condition of Alzheimer's disease. The present invention also relates to a method for the infrared spectroscopic analysis of a blood sample, by means of additionally obtaining at least one spectral value of at least one of the infrared spectrum regions comprised between 1600 and 1700 cm −1 , and/or between 1000 and 1150 cm −1 and/or between 1140 and 1190 cm −1 . Optionally, the Raman spectroscopy method further comprises the infrared spectroscopic analysis of the same blood sample. The invention also relates to a diagnostic method for diagnosing Alzheimer's disease comprising measuring a Raman spectrum and/or an infrared spectrum of a plasma sample. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11598718-B2 |
priorityDate |
2012-08-20^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |