http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015211988-A1

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filingDate 2013-08-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67013d99bf2643e99efae31da2486e97
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publicationDate 2015-07-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2015211988-A1
titleOfInvention Raman, infrared, or raman-infrared analysis of peripheral blood plasma protein structure and its relation to cognitive development in alzheimer's disease
abstract The present invention relates to a Raman spectroscopy method for determining protein structure associated with global cognitive deterioration in Alzheimer's disease from the Raman spectroscopic analysis of a human blood sample, preferably of a human blood plasma sample, comprising obtaining at least one spectral value of at least one of the Raman spectrum regions comprised between 1600-1700 cm −1 , between 910-980 cm −1 , between 730-760 cm −1 and/or between 390-450 cm −1 , and where said spectral value allows obtaining an indication of the presence or absence of protein structure associated with a condition of Alzheimer's disease. The present invention also relates to a method for the infrared spectroscopic analysis of a blood sample, by means of additionally obtaining at least one spectral value of at least one of the infrared spectrum regions comprised between 1600 and 1700 cm −1 , and/or between 1000 and 1150 cm −1 and/or between 1140 and 1190 cm −1 . Optionally, the Raman spectroscopy method further comprises the infrared spectroscopic analysis of the same blood sample. The invention also relates to a diagnostic method for diagnosing Alzheimer's disease comprising measuring a Raman spectrum and/or an infrared spectrum of a plasma sample.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11598718-B2
priorityDate 2012-08-20^^<http://www.w3.org/2001/XMLSchema#date>
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