Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_416cf8b028a73e167af3e062997bdc52 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2014-06-13^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ece3bac47df74d440f37bdf82de73e1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fefd622c52563563169a98006c1ed1af |
publicationDate |
2015-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015330990-A1 |
titleOfInvention |
Method of screening candidate biochemical entities targeting a target biochemical entity |
abstract |
Described herein are methods useful for screening candidate biochemical entities targeting a target biochemical entity and methods useful for identifying a binding moiety for a target biochemical entity. The invention provides methods of screening drug candidates targeting a target biomolecule, comprising selecting a drug candidate based on a signal difference between a first signal and a second signal. The signal difference indicates a difference in an in vivo or in vitro pharmacological property. The first signal is produced upon binding between the target biomolecule and a first candidate by contacting the target biomolecule with the first candidate, and the second signal is produced upon binding between the target biomolecule and a second candidate by contacting the target biomolecule with the second candidate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11486881-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938560-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10657525-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10768174-B2 |
priorityDate |
2013-06-13^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |