| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abad10ce1f9a760ce7e188e7382ed6e1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24083 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
2013-09-11^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd3218ca63ca67917f56bbd1f01149ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fc84eddf32360ceefbba734f48e3980
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f11ed5945d0c981cebc0d05bdd35a82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d8cf19a0e0a62dcc7af6cb45511537 |
| publicationDate |
2016-02-11^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016039874-A1 |
| titleOfInvention |
Regulating bacillus anthracis lethal factor activity via an activating epitope region |
| abstract |
Provided are peptides capable of reducing the ability of antibodies to stimulate the activity of B. anthracis lethal factor. These peptides may be used to reduce activity of LF in a sample containing an LF activity enhancing antibody, to prevent the possibility of LF enhanced activity in a sample or subject, or as a therapeutic to reduce LF activity in a subject that may-have one or more antibodies that enhance LF activity. Also, provided are immunogens that may be used in a vaccine to confer protection to a subject. An immunogen does not include a sequence including the wild-type amino acids present in LF residues 677-680, or mutations of amino acids 677-680 that will also generate antibodies that enhance LF activity. |
| priorityDate |
2012-09-11^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |