Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18c82d1d2b41d8cdf62328e00f73eb07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_066af93d226b9a8b1151cb1bc45bd190 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-205 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 |
filingDate |
2015-03-25^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af3469b998626191265d1ebf1b4846d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fbf88baea2db44ce8de98e3feaa3d74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94d269c5fb4796468c1363fb1ceab6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d457bf9f7579c66970d44942ff2b303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7281dd0d9dfd00cfae5b35a16e432377 |
publicationDate |
2017-03-30^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2017088530-A1 |
titleOfInvention |
New vortioxetine intermediate and synthesis process thereof |
abstract |
The present invention provides a new intermediate II and a method for synthesizing the same. The method comprises: (a) firstly diazotizing a compound of formula I as a raw material, and then halogenating to obtain an intermediate II; and (b) reacting the intermediate II with a compound III to obtain a compound IV, hydrolyzing the obtained compound IV directly without being separated to obtain Vortioxetine represented by compound V. The intermediate II can be used for synthesizing Vortioxetine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927089-B2 |
priorityDate |
2014-05-09^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |