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filingDate 2018-06-08^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7588d14d6cc54e0389124d671ff0b7ba
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publicationDate 2018-10-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2018280476-A1
titleOfInvention Diagnostic biomarkers for fibrotic disorders
abstract The present invention provides novel methods of inhibiting fibrosis, as well as methods of treating or inhibiting fibrotic disorders, using BMP9 and/or BMP10 antagonists. The present invention also provides methods of assessing whether a subject has or is at risk of developing a fibrotic disorder by detecting levels of BMP9 and/or BMP10. Further provided are methods of assessing the efficacy of a treatment regimen for treating a fibrotic disorder by detecting and comparing pre-treatment levels of BMP9 and BMP10 with post-treatment levels of BMP9 and BMP10.
priorityDate 2009-05-08^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID116510
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID729230
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3329
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ59750
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ15746
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID26873
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396360
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID110006
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID397778
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24310
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2990
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395153
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395152
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID451910
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF1PI70
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1JTC4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA7ZWZ1
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID91536
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1027762
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID886358
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403790
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100522394
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID120
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCBAG55070
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID855862
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID14066
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398641
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12667
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF1PKH2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID456060
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4033
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403802
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4092
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24586
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP56483
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403801
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB1LIM9
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100038176
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID30323
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419533589
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396384
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP02544

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