http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018346509-A9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bce595c861dba361078ba893e4713be |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 |
| filingDate | 2016-02-12^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9719f599448230ebe75e3e072760bbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d83259713928a83a8b9bc7ad3554559 |
| publicationDate | 2018-12-06^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2018346509-A9 |
| titleOfInvention | Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis |
| abstract | The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10786517-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11384115-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11612609-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844089-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406646-B2 |
| priorityDate | 2004-10-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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