| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c7c6b46c3f886e76f7ae13540f485b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e381bf98ecdc3155c1bd96f27478ccc3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2521-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0643 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2017-09-29^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee3bcb96f5b7d523a8b266ca1bcfddc6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5b43642f6209a057b50b8bff178e668
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1c661b23a143a0906f2b0b1e85d1fe3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87fa6a81125eb97781d6b6e8742fbd10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a735a9d507fb4ffb49e61411375d3ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae527a9cc6f6758b5e11ba1a26dc694f |
| publicationDate |
2019-02-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2019055510-A1 |
| titleOfInvention |
Well plate-based perfusion culture model of endosteal-extracellular matrix (ecm)-and endothelial-myeloma interactions and methods for testing personalized therapeutics for multiple myeloma |
| abstract |
The described invention provides a well plate-based perfusion culture model of endosteal-, extracellular matrix (ECM)- and endothelial-myeloma interactions and patient-specific methods for selecting treatment for and assessing drug resistance of multiple myeloma (MM). The described methods utilize an ex vivo three dimensional endosteal microenvironment effective to recapitulate spatial and temporal characteristics of a multiple myeloma cancer niche and to maintain viability of multiple myeloma cells (MMCs) obtained from a patient suffering from MM. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021026373-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11421194-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114699404-A |
| priorityDate |
2016-09-29^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |