http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019241890-A1

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filingDate 2018-09-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d31ae8d476391203d2866e133eee5fe
publicationDate 2019-08-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2019241890-A1
titleOfInvention Methods and compositions for manipulating translation of protein isoforms from alternative initiation start sites
abstract Provided herein are antisense oligonucleotides, compositions comprising antisense oligonucleotides, and methods for the use of antisense oligonucleotides in manipulating translation. Expression of isoforms of proteins expressed from different start codons of the same transcript are inhibited by antisense oligonucleotides, which may also enhance expression of non-target isoforms.
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