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publicationDate 2019-08-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2019246907-A1
titleOfInvention Devices, Methods, and Systems for Detection of Collagen Tissue Features
abstract The present application discloses methods, devices, and systems for generating spatially-resolved quantification of cross-linking in cartilage based on Raman scattering of excitation light. The examples presented demonstrate that the method provides a discriminating power sufficient to distinguish early onset of osteo-arthritis even before a patient is symptomatic.
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