| abstract |
Provided is a composition for preventing or treating a metabolic disease or muscle disease, which includes vesicles derived from bacteria of the genus Lactobacillus . Confirmed, when vesicles derived from bacteria of the genus Lactobacillus were administered into an animal model with a metabolic disease caused by a high fat, the vesicles effectively inhibit metabolic diseases caused by a high fat diet, and increase homeostasis to metabolic stress by activating AMPK signaling in myocytes, and therefore, the vesicles derived from bacteria of the genus Lactobacillus according to the presently claimed subject matter can be effectively used in development of pharmaceuticals or health functional foods for preventing, improving symptoms or treating metabolic diseases such as obesity and muscle diseases. |