| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
2022-05-13^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d10490329d17a47495bac41fd72de520
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75b538f275a314d8a22dcf3c3c183756
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1909a0a0cfd2335de97542395a5d9cb0 |
| publicationDate |
2022-10-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022324913-A1 |
| titleOfInvention |
Antigenic neuron specific enolase peptides for diagnosing and treating autism |
| abstract |
The present disclosure provides peptides that specifically bind to maternal autoantibodies that are generated in the mother or potential mother against the endogenous polypeptide antigen neuron specific enolase (NSE) protein. The peptides described herein are useful for determining a risk of an offspring for developing an autism spectrum disorder (ASD) by detecting the presence of maternal autoantibodies in a biological sample of the mother or potential mother. The peptides or mimotopes thereof can also be administered to the mother or potential mother to block the binding between maternal autoantibodies and their antigens, thereby neutralizing the maternal autoantibodies. |
| priorityDate |
2019-11-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |