| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc9a254a3e08470fbd55ba3b00cf3f43 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 |
| filingDate |
2022-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1802f9d15bd3b8cbedf270298510e6ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af6a2877e23c434f6eeb3b7fffd04ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d765f160233ce9436cbde928f8898acc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_240422a6a152e310f6a47ccb9f1f3134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2c5218919743906f9b8ebd169d781a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ea9b7d518a5fd1d3fc889203251d5e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_719b5fe5a402e990de699ee15d15c0cb |
| publicationDate |
2022-12-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2022389436-A1 |
| titleOfInvention |
Methods to prevent rapid silencing of genes in pluripotent stem cells |
| abstract |
Provided herein are methods of producing cell lines with stable expression of a transgene by removal of CpG motifs. In further methods, there are provided methods for cell lines with stable expression of a transgene by driving expression by novel promoters or by tagging endogenous genes. |
| priorityDate |
2021-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |