http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3853904-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate | 1973-08-07^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1974-12-10^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b27b04d28d06661e0cd75ec44f46be9 |
| publicationDate | 1974-12-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3853904-A |
| titleOfInvention | DIBENZA-{8 b,f{9 -S-TRIAZOLO-{8 4,3-d{9 {8 1,4{9 OXAZEPIN-3-(2H)-ONES |
| abstract | Compounds of the formula III: wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, inclusive and IN WHICH R7 and R8 are hydrogen and alkyl, as defined above and n is 2 or 3, or together IS PYRROLIDINO, PIPERIDINO OR N-methylpiperazino; wherein R3 and R4 are hydrogen, fluoro, chloro, bromo, nitro, alkyl defined as above, trifluoromethyl, or alkoxy, of 1 to 3 carbon atoms, inclusive, are prepared by reacting a thio compound of formula I: wherein R3 and R4 are defined as above, in sequence; 1. WITH AN ALKYLCARBAZATE; AND THE RESULTING INTERMEDIATE PRODUCT II 2. with an alkylating agent of the formula R1''X in which R1'' is alkyl, AS DEFINED ABOVE AND X is chlorine, bromine, or iodine, to obtain a compound III as defined above. Compounds of formula III and the pharmacologically acceptable acid addition salts thereof have anti-depressant activity and tranquilizing activity and can be used in mammals. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4002639-A |
| priorityDate | 1972-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 111 of 111.