abstract |
Derivatives of digoxigenin which are either unlabeled or radioiodinated having the following structural formula: WHEREIN R'' is hydroxyl or acetoxy; B is succinyl, phthaloyl, maleyl or fumaryl, preferably succinyl, and X is hydroxyl or alkali metal salt thereof; a protein conjugate; a peptide conjugate; or an amino acid or amino acid ester radical. The radiolabeled compounds are used in the radioimmunological assay of digoxin. The preferred compound is radioiodinated 3succinyl digoxigenin-L-tyrosine. |