abstract |
New prostaglandin analogues having therapeutic utility of the formula: ##SPC1## n (wherein B is a grouping of the formula: ##SPC2## n X is --CH 2 CH 2 -- or cis --CH=CH--, Y is trans --CH=CH-- or, when X is --CH 2 CH 2 --, Y is additionally --CH 2 CH 2 --, A is alkyl of 1 through 3 carbon atoms, n is 4 or 5, and indicates attachment of the hydroxy radical to the carbon atom in alpha or beta configuration), and alkyl esters thereof, and cyclodextrin clathrates of such acids and esters, and non-toxic salts of such acids. |