abstract |
Amines of the formula ##SPC1## n Wherein R 1 is lower alkyl, lower alkoxy or amino, R 2 is hydrogen or lower alkyl, R 3 is hydrogen, lower alkyl, carboxyl or lower alkoxycarbonyl, R 4 is hydrogen or lower alkyl, R 5 is lower alkyl, aryl-lower alkyl or optionally functionally modified carboxy-lower alkyl and R 6 denotes halogen, trifluoromethyl, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, nitro, lower alkoxymethyl, carbamoyl, N-lower alkylcarbamoyl, nitrile, lower alkinyloxy or hydrogen, and their salts block cardiac and vascular β-receptors the are useful in the treatment of arrhythenias and angina pectoris and as intermediates for, especially for pharmaceutically active substances. |