http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4062844-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04
filingDate 1976-09-20^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1977-12-13^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed6735dc426c6717ec8b04c2e9ee95a0
publicationDate 1977-12-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4062844-A
titleOfInvention Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines
abstract Certain 2-(4-aroylpiperazin-1-yl)-4-amino-6,7-dimethoxyquinazolines are prepared by a novel process wherein certain 2-(4-substituted-piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline intermediates wherein said substituent is cyano, certain carbon-oxygen double bond containing groups or certain carbon-nitrogen double bond containing groups, are reacted with certain metalloaryl compounds followed by hydrolysis. The products are known hypotensive agents. Certain of the process intermediates are novel compounds.
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priorityDate 1976-09-20^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21393369
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11007813
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID223737908
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414028427
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7513
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID8431
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID128917894
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID127398044
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID8909
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