| abstract |
A novel 3-endo-protected hydroxyl-tricyclo[3,2,0,0 2 ,7 ]-heptan-6-one is described which can be alkylated stereospecifically to give a 5-endo-protected hydroxyl-bicyclo [2,2,1]heptan-2-one which may then be converted via a sequence of reactions into prostaglandins of the F-series having a protecting group at the 9-position. The synthesis of the tricyclo[3,2,0,0 2 ,7 ]heptan-6-one is also described. |