http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4136183-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 |
| filingDate | 1976-08-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-01-23^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1ecdef04c563cda65cc6d0e4f75c8dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b6cb5a09d0e3c98b8969b885990f48 |
| publicationDate | 1979-01-23^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4136183-A |
| titleOfInvention | Benzopyranopyridines as antiglaucoma agents |
| abstract | A method of reducing intra-ocular pressure in mammalian patients comprising administering to a glaucoma patient a therapeutically effective amount of a compound of the formula ##STR1## WHEREIN, IN THE C ring, X is CH 2 , S, ##STR2## or NR 4 where R 4 is H, loweralkyl, loweralkenyl, loweralkynyl or loweralkanoyl; n is an integer of 0 to 3; m is an integer of 0 to 3, or the C ring is a quinuclidine ring ##STR3## each R 1 is loweralkyl, and when taken together, the substituents R 1 R 1 form oxygen; R 2 is a C 1 -C 20 straight or branched chain alkyl, cycloalkyl, or wherein Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms, and each R 5 , R 6 and R 7 are the same or different members of the group consisting of H, halo or loweralkyl; R 3 is H or ##STR4## WHEREIN Y' is a straight or branched chain alkylene group having 1 to 8 carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH 2 , O, S or NR 9 where R 9 is H or loweralkyl, with the provision that when Z is O, S or NR 9 , the sum of a and b is 3 or 4, and R 8 is H or loweralkyl; and the pharmaceutically acceptable salts thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018208910-A1 |
| priorityDate | 1976-08-04^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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