| abstract |
Two, preferably three, layered orally administrable granules containing orally administrable penicillins have desirable properties such as elegance, freedom from dust and good reconstitution. They contain an inert core, preferably of sucrose, a penicillin/binder first layer and normally and preferably a final coating layer of conventional additives such as dyes, flavors etc.. Preferably the penicillin is amoxycillin trihydrate and the binder sucrose. The granules may be prepared by fluid bed granulation. |