| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-59 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
| filingDate |
1977-04-05^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1980-06-17^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f31f72572a296b361b9f45f8addf12f5 |
| publicationDate |
1980-06-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4208515-A |
| titleOfInvention |
3-Halo cephalosporins |
| abstract |
7-Acylamido- and 7-amino-3-halo-3-cephem-4-carboxylic acids, esters and pharmaceutically-acceptable salts and esters thereof are new cephalosporin compounds provided by the reaction of a 7-acylamido-3-hydroxy-3-cephem-4-carboxylic acid ester or a 7-amino-3-hydroxy-3-cephem-4-carboxylic acid ester with an iodinating, fluorinating, chlorinating, or brominating reagent. For example, 7-amino-3-chloro-3-cephem-4-carboxylic acid and 7-phenoxyacetamido-3-chloro-3-cephem-4-carboxylic acid are provided. The 7-acylamido-3-halo cephalosporin acids and pharmaceutically acceptable salts and esters provided are valuable antibiotic compounds having desirable therapeutic properties. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4281116-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5578721-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5604222-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0348124-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014350240-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0348124-A3 |
| priorityDate |
1973-02-23^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |