abstract |
A drug delivery system is disclosed useful for controlled ocular therapy. The system is manufactured as an ocular insert, and it comprises a beta-adrenergic blocking osmotic solute and a parasympathomimetic osmotic solute dispersed in a polymer with the solutes surrounded by the polymer. The system, when placed in the eye, delivers both drugs at a controlled rate over time. A method also is disclosed for the management of intraocular pressure using the ocular system. |