| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c1b662dc0dc2b094c71df74b771bbbb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-06 |
| filingDate |
1979-09-19^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1981-12-29^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ce468bca58cc7ef9def4796c94ab176
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bed742ad43692e764a40c37aa4811584 |
| publicationDate |
1981-12-29^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4308376-A |
| titleOfInvention |
Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals |
| abstract |
O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to prepare 2-amino-2-deoxy sugars, such as D-galactosamine and lactosamine. The O-acetylated 2-azido-2-deoxy glycosyl nitrates can alternately be converted to O-acetylated 2-azido-2-deoxy glycosyl halides which are useful in the preparation of O-acetylated 2-azido-2-deoxy glycosides, which in turn can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which efficiently and preferentially absorb anti-A antibodies from blood plasma. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5141648-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6034055-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5527891-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4935503-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5541294-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5278301-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6013779-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5905071-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4442284-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5837830-A |
| priorityDate |
1977-04-14^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |