| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4589b30807b53be5b8d5c09bfad19dc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-08 |
| filingDate |
1985-08-19^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1986-12-09^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd9f18160bb0e8caf1ef7f007970e50c |
| publicationDate |
1986-12-09^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4628090-A |
| titleOfInvention |
Fluorine-containing antifolates incapable of polyglutanayte formation related compounds |
| abstract |
A methotrexate derivative having the following general formula is incapable of forming polyglutamate and thus is expected to have reduced cytotoxicity associated with the formation of polyglutamate derivatives in a living cell, ##STR1## wherein n is from 0 to 5. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5286726-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8904312-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013026842-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4996207-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8344140-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5760229-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010111863-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010111864-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5073554-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961246-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10377756-B2 |
| priorityDate |
1984-08-21^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |