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publicationDate 1987-01-06^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4634706-A
titleOfInvention Griseolic acid derivatives, and their use as enzyme inhibitors
abstract Griseolic acid derivatives of formula (I): <IMAGE> (I) wherein A represents: <IMAGE> have enzyme-inhibitory activity, especially against cAMP PDE and cGMP PDE. When formulated as compositions with appropriate carriers or diluents, they may be used for the treatment of a variety of organic disorders and show toxicities less than griseolic acid itself.
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