http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4786645-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e759368252958400591adc79b18e9bb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
filingDate | 1987-07-02^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1988-11-22^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0a72e0ec44d1f6a7ed46dbcf0b6d82f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa803270dc5ab77b83fc2f45135c9f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_106f1006dc2a530b6d9e824441d806c3 |
publicationDate | 1988-11-22^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4786645-A |
titleOfInvention | 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical compositions |
abstract | A compound of the general formula I: <IMAGE> (I) in which Ar is a pyridyl, quinolinyl, isoquinolinyl, naphthyridinyl, pyrimidyl, quinazolinyl, thiazolyl, benzothiazolyl, imidazolyl, benzimidazolyl, oxazolyl, benzoxazolyl, thienyl, benzothienyl or naphthyl group; optionally substituted with one or more halogen or alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, alkylsulphinyl, alkylsulphonyl, sulphamido, alkylsulphamido, dialkylsulphamido, alkylcarbonyl, benzoyl, alkyloxycarbonyl, carboxy, phenoxycarbonyl, alkylcabonyloxy, benzoyloxy, alkylcarbonylamino, benzamido, phenyl, benzyl, phenoxy or phenylthio group, provided that (i) when Ar is a pyridyl group, the pyridyl group must be substituted, (ii) an alkyl moiety contains 1 to 4 straight- or branched chain carbon atoms; (iii) a phenyl moiety may be unsubstituted or substituted with one or more halogen or alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, phenyl or benzyl group in separate enantiomeric form or mixtures thereof, or a pharmaceutically acceptable salt thereof is useful in the treatment of all pathological conditions in which PAF-acether may be implicated directly or indirectly. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5086051-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5120751-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5120749-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9214732-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5149704-A |
priorityDate | 1986-07-04^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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