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filingDate 1987-06-26^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1989-11-07^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92fb9f067467b942d919a5ccc35abf01
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publicationDate 1989-11-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4879376-A
titleOfInvention Triterpene saponins having anti-inflammatory, mucolytic and antiedemic activities, process for the preparation thereof and pharmaceutical compositions containing them
abstract Triterpene saponins of formula <IMAGE> wherein R1 is H or OH and R2 is a tetrasaccharide, or alternatively pentasaccharide, chain have antiinflammatory, mucolytic and antiedemic activities. Said saponins are isolated from roots and bark of Crossopteryx febrifuga, for instance by precipitating them, in form of a complex with cholesterol or sytosterol, from an alcoholic extract of the vegetal material and by partitioning the precipitate between an apolar solvent, which subtracts the complexing agent and a polar solvent in which saponins are soluble.
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